BDBM50452899 CHEMBL4215012
SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6@@H](-[#8]-[#6]-1=O)-c1ccccc1-[#8]
InChI Key: InChIKey=GQRGTIMUCZUFJO-NXZBIGBUSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Sus scrofa) | BDBM50452899 (CHEMBL4215012) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of pig liver microsomal HMG-CoA reductase by colorimetric method | J Med Chem 61: 3609-3625 (2018) Article DOI: 10.1021/acs.jmedchem.8b00107 BindingDB Entry DOI: 10.7270/Q2ZS3045 | |||||||||||
More data for this Ligand-Target Pair |