BDBM50454583 CHEMBL4205996

SMILES: OC(=O)c1cc(Cl)ccc1NC(=O)COc1cccc(c1)-c1ccoc1

InChI Key: InChIKey=BKOKVEAXWGGKAT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator inhibitor-1 (Homo sapiens (Human))	BDBM50454583 (CHEMBL4205996) Show SMILES OC(=O)c1cc(Cl)ccc1NC(=O)COc1cccc(c1)-c1ccoc1 Show InChI InChI=1S/C19H14ClNO5/c20-14-4-5-17(16(9-14)19(23)24)21-18(22)11-26-15-3-1-2-12(8-15)13-6-7-25-10-13/h1-10H,11H2,(H,21,22)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hamari Chemicals, Ltd. Curated by ChEMBL					Assay Description Inhibition of human PAI-1 assessed as remaining enzyme activity by measuring p-nitroaniline release pre-incubated for 15 mins before 9.8 nM human tPA...				Bioorg Med Chem Lett 28: 809-813 (2018) Article DOI: 10.1016/j.bmcl.2017.11.016 BindingDB Entry DOI: 10.7270/Q2TH8Q90
					More data for this Ligand-Target Pair