BDBM50457830 CHEMBL4211826

SMILES: C[C@H](C(=O)N1CCC(CC1)Oc1ccc(cc1C(N)=O)-c1cn(C)cn1)c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=ODHHGNXLHJYSLD-INIZCTEOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457830   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50457830 (CHEMBL4211826) Show SMILES C[C@H](C(=O)N1CCC(CC1)Oc1ccc(cc1C(N)=O)-c1cn(C)cn1)c1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C26H27F3N4O4/c1-16(17-3-6-20(7-4-17)37-26(27,28)29)25(35)33-11-9-19(10-12-33)36-23-8-5-18(13-21(23)24(30)34)22-14-32(2)15-31-22/h3-8,13-16,19H,9-12H2,1-2H3,(H2,30,34)/t16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by fluorescence polarization assay				J Med Chem 61: 6779-6800 (2018) Article DOI: 10.1021/acs.jmedchem.8b00633 BindingDB Entry DOI: 10.7270/Q2K64MPW
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50457830 (CHEMBL4211826) Show SMILES C[C@H](C(=O)N1CCC(CC1)Oc1ccc(cc1C(N)=O)-c1cn(C)cn1)c1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C26H27F3N4O4/c1-16(17-3-6-20(7-4-17)37-26(27,28)29)25(35)33-11-9-19(10-12-33)36-23-8-5-18(13-21(23)24(30)34)22-14-32(2)15-31-22/h3-8,13-16,19H,9-12H2,1-2H3,(H2,30,34)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at prolink-tagged TrkA in human U2OS cells assessed as inhibition of beta-NGF-induced receptor phosphorylation by measuring reduc...				J Med Chem 61: 6779-6800 (2018) Article DOI: 10.1021/acs.jmedchem.8b00633 BindingDB Entry DOI: 10.7270/Q2K64MPW
					More data for this Ligand-Target Pair