BDBM50473797 CHEMBL105674

SMILES: CCOC(=O)c1c(C)[nH]c2ccc3OC4N(CCc5cc(Cl)ccc45)Cc3c12

InChI Key: InChIKey=BRKQBHOIDPLFHE-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50473797   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50473797 (CHEMBL105674) Show SMILES CCOC(=O)c1c(C)[nH]c2ccc3OC4N(CCc5cc(Cl)ccc45)Cc3c12 Show InChI InChI=1S/C22H21ClN2O3/c1-3-27-22(26)19-12(2)24-17-6-7-18-16(20(17)19)11-25-9-8-13-10-14(23)4-5-15(13)21(25)28-18/h4-7,10,21,24H,3,8-9,11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	363	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human muscarinic acetylcholine receptor M4 in transfected CHO cells.				J Med Chem 45: 3094-102 (2002) Article DOI: 10.1021/jm011116o BindingDB Entry DOI: 10.7270/Q2BZ68S8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50473797 (CHEMBL105674) Show SMILES CCOC(=O)c1c(C)[nH]c2ccc3OC4N(CCc5cc(Cl)ccc45)Cc3c12 Show InChI InChI=1S/C22H21ClN2O3/c1-3-27-22(26)19-12(2)24-17-6-7-18-16(20(17)19)11-25-9-8-13-10-14(23)4-5-15(13)21(25)28-18/h4-7,10,21,24H,3,8-9,11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human muscarinic acetylcholine receptor M3 in transfected CHO cells.				J Med Chem 45: 3094-102 (2002) Article DOI: 10.1021/jm011116o BindingDB Entry DOI: 10.7270/Q2BZ68S8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50473797 (CHEMBL105674) Show SMILES CCOC(=O)c1c(C)[nH]c2ccc3OC4N(CCc5cc(Cl)ccc45)Cc3c12 Show InChI InChI=1S/C22H21ClN2O3/c1-3-27-22(26)19-12(2)24-17-6-7-18-16(20(17)19)11-25-9-8-13-10-14(23)4-5-15(13)21(25)28-18/h4-7,10,21,24H,3,8-9,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M2 in transfected CHO cells.				J Med Chem 45: 3094-102 (2002) Article DOI: 10.1021/jm011116o BindingDB Entry DOI: 10.7270/Q2BZ68S8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50473797 (CHEMBL105674) Show SMILES CCOC(=O)c1c(C)[nH]c2ccc3OC4N(CCc5cc(Cl)ccc45)Cc3c12 Show InChI InChI=1S/C22H21ClN2O3/c1-3-27-22(26)19-12(2)24-17-6-7-18-16(20(17)19)11-25-9-8-13-10-14(23)4-5-15(13)21(25)28-18/h4-7,10,21,24H,3,8-9,11H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human muscarinic acetylcholine receptor M1 in transfected CHO cells.				J Med Chem 45: 3094-102 (2002) Article DOI: 10.1021/jm011116o BindingDB Entry DOI: 10.7270/Q2BZ68S8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50473797 (CHEMBL105674) Show SMILES CCOC(=O)c1c(C)[nH]c2ccc3OC4N(CCc5cc(Cl)ccc45)Cc3c12 Show InChI InChI=1S/C22H21ClN2O3/c1-3-27-22(26)19-12(2)24-17-6-7-18-16(20(17)19)11-25-9-8-13-10-14(23)4-5-15(13)21(25)28-18/h4-7,10,21,24H,3,8-9,11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human muscarinic acetylcholine receptor M5 in transfected CHO cells.				J Med Chem 45: 3094-102 (2002) Article DOI: 10.1021/jm011116o BindingDB Entry DOI: 10.7270/Q2BZ68S8
					More data for this Ligand-Target Pair