null

SMILES: CCCc1[nH]c2ccc3OC4N(CCc5cc(SC)ccc45)Cc3c2c1C(=O)OCC

InChI Key: InChIKey=COXRSODPRFBGSM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50473815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50473815 (CHEMBL104693) Show SMILES CCCc1[nH]c2ccc3OC4N(CCc5cc(SC)ccc45)Cc3c2c1C(=O)OCC Show InChI InChI=1S/C25H28N2O3S/c1-4-6-19-23(25(28)29-5-2)22-18-14-27-12-11-15-13-16(31-3)7-8-17(15)24(27)30-21(18)10-9-20(22)26-19/h7-10,13,24,26H,4-6,11-12,14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human muscarinic acetylcholine receptor M4 in transfected CHO cells.				J Med Chem 45: 3094-102 (2002) Article DOI: 10.1021/jm011116o BindingDB Entry DOI: 10.7270/Q2BZ68S8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50473815 (CHEMBL104693) Show SMILES CCCc1[nH]c2ccc3OC4N(CCc5cc(SC)ccc45)Cc3c2c1C(=O)OCC Show InChI InChI=1S/C25H28N2O3S/c1-4-6-19-23(25(28)29-5-2)22-18-14-27-12-11-15-13-16(31-3)7-8-17(15)24(27)30-21(18)10-9-20(22)26-19/h7-10,13,24,26H,4-6,11-12,14H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human muscarinic acetylcholine receptor M3 in transfected CHO cells.				J Med Chem 45: 3094-102 (2002) Article DOI: 10.1021/jm011116o BindingDB Entry DOI: 10.7270/Q2BZ68S8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50473815 (CHEMBL104693) Show SMILES CCCc1[nH]c2ccc3OC4N(CCc5cc(SC)ccc45)Cc3c2c1C(=O)OCC Show InChI InChI=1S/C25H28N2O3S/c1-4-6-19-23(25(28)29-5-2)22-18-14-27-12-11-15-13-16(31-3)7-8-17(15)24(27)30-21(18)10-9-20(22)26-19/h7-10,13,24,26H,4-6,11-12,14H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	871	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human muscarinic acetylcholine receptor M1 in transfected CHO cells.				J Med Chem 45: 3094-102 (2002) Article DOI: 10.1021/jm011116o BindingDB Entry DOI: 10.7270/Q2BZ68S8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50473815 (CHEMBL104693) Show SMILES CCCc1[nH]c2ccc3OC4N(CCc5cc(SC)ccc45)Cc3c2c1C(=O)OCC Show InChI InChI=1S/C25H28N2O3S/c1-4-6-19-23(25(28)29-5-2)22-18-14-27-12-11-15-13-16(31-3)7-8-17(15)24(27)30-21(18)10-9-20(22)26-19/h7-10,13,24,26H,4-6,11-12,14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M2 in transfected CHO cells.				J Med Chem 45: 3094-102 (2002) Article DOI: 10.1021/jm011116o BindingDB Entry DOI: 10.7270/Q2BZ68S8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50473815 (CHEMBL104693) Show SMILES CCCc1[nH]c2ccc3OC4N(CCc5cc(SC)ccc45)Cc3c2c1C(=O)OCC Show InChI InChI=1S/C25H28N2O3S/c1-4-6-19-23(25(28)29-5-2)22-18-14-27-12-11-15-13-16(31-3)7-8-17(15)24(27)30-21(18)10-9-20(22)26-19/h7-10,13,24,26H,4-6,11-12,14H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human muscarinic acetylcholine receptor M5 in transfected CHO cells.				J Med Chem 45: 3094-102 (2002) Article DOI: 10.1021/jm011116o BindingDB Entry DOI: 10.7270/Q2BZ68S8
					More data for this Ligand-Target Pair