BDBM50474908 CHEMBL191001

SMILES: [H][C@@]1(CC[C@]2(C)C3CCC4C(C)(C)C(=O)C(=C[C@]4(C)C3=CC[C@]12C)C#N)[C@H](C)CC[C@@H](O)C(C)(C)O

InChI Key: InChIKey=KBZDSAIJDPOESJ-GCWQWUROSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50474908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase II (Homo sapiens (Human))	BDBM50474908 (CHEMBL191001) Show SMILES [H][C@@]1(CC[C@]2(C)C3CCC4C(C)(C)C(=O)C(=C[C@]4(C)C3=CC[C@]12C)C#N)[C@H](C)CC[C@@H](O)C(C)(C)O |c:15,21| Show InChI InChI=1S/C31H47NO3/c1-19(9-12-25(33)28(4,5)35)21-13-15-31(8)23-10-11-24-27(2,3)26(34)20(18-32)17-29(24,6)22(23)14-16-30(21,31)7/h14,17,19,21,23-25,33,35H,9-13,15-16H2,1-8H3/t19-,21-,23?,24?,25-,29-,30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Osaka University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against human DNA topoisomerase II				Bioorg Med Chem Lett 15: 2966-9 (2005) Article DOI: 10.1016/j.bmcl.2005.04.052 BindingDB Entry DOI: 10.7270/Q2NZ8BDQ
					More data for this Ligand-Target Pair