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BDBM50482558 HIPPURISTANOHEMIACETAL::Hippuristanohemiacetal

SMILES: [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@@H](CC[C@]5(C)[C@@]4([H])[C@@H](O)C[C@@]33[C@H](O)O[C@](C)([C@@]13[H])[C@@]1(C[C@H](C)C(C)(C)O1)O2)OC(C)=O

InChI Key: InChIKey=QIIQIIUEZGRUMJ-IXDUNUBMSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50482558   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Eukaryotic initiation factor 4A-I


(Homo sapiens (Human))		BDBM50482558
PNG
(HIPPURISTANOHEMIACETAL | Hippuristanohemiacetal)
Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@@H](CC[C@]5(C)[C@@]4([H])[C@@H](O)C[C@@]33[C@H](O)O[C@](C)([C@@]13[H])[C@@]1(C[C@H](C)C(C)(C)O1)O2)OC(C)=O |r|
Show InChI InChI=1S/C30H46O7/c1-15-13-30(37-26(15,3)4)28(6)24-22(35-30)12-20-19-8-7-17-11-18(34-16(2)31)9-10-27(17,5)23(19)21(32)14-29(20,24)25(33)36-28/h15,17-25,32-33H,7-14H2,1-6H3/t15-,17-,18+,19-,20-,21-,22-,23+,24+,25+,27-,28+,29+,30-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.10E+4n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...

Nat Chem Biol 2: 213-20 (2006)


Article DOI: 10.1038/nchembio776
BindingDB Entry DOI: 10.7270/Q2F47RZB
More data for this
Ligand-Target Pair