null
SMILES: COc1cc2nc(NCCCN(C)C)nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC
InChI Key: InChIKey=YYFDMPHIONBOKZ-UHFFFAOYSA-N
PDB links: 2 PDB IDs match this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
REST corepressor 1 (Homo sapiens (Human)) | BDBM50507295 (CHEMBL1232432) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid PDB UniChem | PDB | n/a | n/a | n/a | 243 | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50507295 (CHEMBL1232432) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 243 | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University Curated by ChEMBL | Assay Description Binding affinity to LSD1 (unknown origin) | Eur J Med Chem 162: 555-567 (2019) Article DOI: 10.1016/j.ejmech.2018.11.035 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |