BDBM50511421 CHEMBL4439287
SMILES: CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncnc3n(ccc23)-c2ccc(C)cc2)c1
InChI Key: InChIKey=QSHQSGKUSRNJPU-VMPITWQZSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatidylinositol-5-phosphate 4-kinase type-2 beta (Homo sapiens (Human)) | BDBM50511421 (CHEMBL4439287) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Curated by ChEMBL | Assay Description Inhibition of PI5P4Kbeta (unknown origin) incubated for 15 mins in presence of ATP by ADP-Glo assay | ACS Med Chem Lett 11: 346-352 (2020) Article DOI: 10.1021/acsmedchemlett.9b00402 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha (Homo sapiens) | BDBM50511421 (CHEMBL4439287) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute Curated by ChEMBL | Assay Description Inhibition of PI5P4Kalpha (unknown origin) incubated for 15 mins in presence of ATP by ADP-Glo assay | ACS Med Chem Lett 11: 346-352 (2020) Article DOI: 10.1021/acsmedchemlett.9b00402 | |||||||||||
More data for this Ligand-Target Pair |