BDBM50521625 CHEMBL4465853

SMILES: CCN1CCN(CC1)c1cc(Nc2ncc(s2)-c2ccc(NC(=O)Nc3cc(CC)on3)nc2)ncn1

InChI Key: InChIKey=ANSBRKRKQZNXNT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521625   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50521625 (CHEMBL4465853) Show SMILES CCN1CCN(CC1)c1cc(Nc2ncc(s2)-c2ccc(NC(=O)Nc3cc(CC)on3)nc2)ncn1 Show InChI InChI=1S/C24H28N10O2S/c1-3-17-11-21(32-36-17)30-23(35)29-19-6-5-16(13-25-19)18-14-26-24(37-18)31-20-12-22(28-15-27-20)34-9-7-33(4-2)8-10-34/h5-6,11-15H,3-4,7-10H2,1-2H3,(H,26,27,28,31)(H2,25,29,30,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 6x-His-tagged c-KIT (547 to 935 residues)/(694 to 753 residues deletion) expressed in baculovirus infected...				J Med Chem 62: 3940-3957 (2019) Article DOI: 10.1021/acs.jmedchem.8b01845
					More data for this Ligand-Target Pair