BDBM50521633 CHEMBL4545864

SMILES: CCN1CCN(CC1)c1cc(Nc2ncc(CCCNC(=O)Nc3cc(CC)on3)s2)nc(C)n1

InChI Key: InChIKey=KTODMAVSACJCDO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50521633 (CHEMBL4545864) Show SMILES CCN1CCN(CC1)c1cc(Nc2ncc(CCCNC(=O)Nc3cc(CC)on3)s2)nc(C)n1 Show InChI InChI=1S/C23H33N9O2S/c1-4-17-13-20(30-34-17)28-22(33)24-8-6-7-18-15-25-23(35-18)29-19-14-21(27-16(3)26-19)32-11-9-31(5-2)10-12-32/h13-15H,4-12H2,1-3H3,(H2,24,28,30,33)(H,25,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 6x-His-tagged c-KIT (547 to 935 residues)/(694 to 753 residues deletion) expressed in baculovirus infected...				J Med Chem 62: 3940-3957 (2019) Article DOI: 10.1021/acs.jmedchem.8b01845
					More data for this Ligand-Target Pair