BDBM50529787 CHEMBL4572126

SMILES: Cc1ccc(cc1-c1ccc2c(n[nH]c2c1)-c1cnn(CCO)c1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=FNKHCCNFMOPNQT-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50529787 (CHEMBL4572126) Show SMILES Cc1ccc(cc1-c1ccc2c(n[nH]c2c1)-c1cnn(CCO)c1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H22F3N5O2/c1-16-5-6-18(26(37)32-21-4-2-3-20(13-21)27(28,29)30)11-23(16)17-7-8-22-24(12-17)33-34-25(22)19-14-31-35(15-19)9-10-36/h2-8,11-15,36H,9-10H2,1H3,(H,32,37)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of FGFR1 (unknown origin) after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50529787 (CHEMBL4572126) Show SMILES Cc1ccc(cc1-c1ccc2c(n[nH]c2c1)-c1cnn(CCO)c1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H22F3N5O2/c1-16-5-6-18(26(37)32-21-4-2-3-20(13-21)27(28,29)30)11-23(16)17-7-8-22-24(12-17)33-34-25(22)19-14-31-35(15-19)9-10-36/h2-8,11-15,36H,9-10H2,1H3,(H,32,37)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DDR2 (unknown origin) using poly (Glu, Tyr) 4:1 substrate after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50529787 (CHEMBL4572126) Show SMILES Cc1ccc(cc1-c1ccc2c(n[nH]c2c1)-c1cnn(CCO)c1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H22F3N5O2/c1-16-5-6-18(26(37)32-21-4-2-3-20(13-21)27(28,29)30)11-23(16)17-7-8-22-24(12-17)33-34-25(22)19-14-31-35(15-19)9-10-36/h2-8,11-15,36H,9-10H2,1H3,(H,32,37)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of FGFR1 (unknown origin) after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50529787 (CHEMBL4572126) Show SMILES Cc1ccc(cc1-c1ccc2c(n[nH]c2c1)-c1cnn(CCO)c1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H22F3N5O2/c1-16-5-6-18(26(37)32-21-4-2-3-20(13-21)27(28,29)30)11-23(16)17-7-8-22-24(12-17)33-34-25(22)19-14-31-35(15-19)9-10-36/h2-8,11-15,36H,9-10H2,1H3,(H,32,37)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DDR2 (unknown origin) using poly (Glu, Tyr) 4:1 substrate after 60 mins by ELISA				Eur J Med Chem 163: 671-689 (2019) Article DOI: 10.1016/j.ejmech.2018.12.015
					More data for this Ligand-Target Pair