BDBM50529816 CHEMBL4529234

SMILES: COc1ccc(Cn2cc(nn2)C(=O)N\N=C2\C(=O)Nc3c2cccc3C)cc1

InChI Key: InChIKey=YYGUFPVMOAZQNZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP/microtubule affinity-regulating kinase 4 (Homo sapiens (Human))	BDBM50529816 (CHEMBL4529234) Show SMILES COc1ccc(Cn2cc(nn2)C(=O)N\N=C2\C(=O)Nc3c2cccc3C)cc1 Show InChI InChI=1S/C20H18N6O3/c1-12-4-3-5-15-17(12)21-20(28)18(15)23-24-19(27)16-11-26(25-22-16)10-13-6-8-14(29-2)9-7-13/h3-9,11H,10H2,1-2H3,(H,24,27)(H,21,23,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Millia Islamia Curated by ChEMBL					Assay Description Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...				Eur J Med Chem 163: 840-852 (2019) Article DOI: 10.1016/j.ejmech.2018.12.026
					More data for this Ligand-Target Pair
MAP/microtubule affinity-regulating kinase 4 (Homo sapiens (Human))	BDBM50529816 (CHEMBL4529234) Show SMILES COc1ccc(Cn2cc(nn2)C(=O)N\N=C2\C(=O)Nc3c2cccc3C)cc1 Show InChI InChI=1S/C20H18N6O3/c1-12-4-3-5-15-17(12)21-20(28)18(15)23-24-19(27)16-11-26(25-22-16)10-13-6-8-14(29-2)9-7-13/h3-9,11H,10H2,1-2H3,(H,24,27)(H,21,23,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Millia Islamia Curated by ChEMBL					Assay Description Inhibition of human recombinant MARK4 expressed in Escherichia coli M15 cells after 2 hrs in presence of [gamma-32-P]ATP by TLC analysis based ATPase...				Eur J Med Chem 163: 840-852 (2019) Article DOI: 10.1016/j.ejmech.2018.12.026
					More data for this Ligand-Target Pair