BDBM50532028 CHEMBL4586820

SMILES: O=C(Cn1nnc(n1)-c1ccccc1)Nc1cc(nn1C1CCCCC1)C1CC1

InChI Key: InChIKey=WIHUNEBYQDWYLW-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50532028 (CHEMBL4586820) Show SMILES O=C(Cn1nnc(n1)-c1ccccc1)Nc1cc(nn1C1CCCCC1)C1CC1 Show InChI InChI=1S/C21H25N7O/c29-20(14-27-25-21(23-26-27)16-7-3-1-4-8-16)22-19-13-18(15-11-12-15)24-28(19)17-9-5-2-6-10-17/h1,3-4,7-8,13,15,17H,2,5-6,9-12,14H2,(H,22,29)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	659	n/a	n/a	n/a	n/a
University of Nebraska Medical Center Curated by ChEMBL					Assay Description Activation of human GIRK1/4 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay				Bioorg Med Chem Lett 29: 791-796 (2019) Article DOI: 10.1016/j.bmcl.2019.01.027
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50532028 (CHEMBL4586820) Show SMILES O=C(Cn1nnc(n1)-c1ccccc1)Nc1cc(nn1C1CCCCC1)C1CC1 Show InChI InChI=1S/C21H25N7O/c29-20(14-27-25-21(23-26-27)16-7-3-1-4-8-16)22-19-13-18(15-11-12-15)24-28(19)17-9-5-2-6-10-17/h1,3-4,7-8,13,15,17H,2,5-6,9-12,14H2,(H,22,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	271	n/a	n/a	n/a	n/a
University of Nebraska Medical Center Curated by ChEMBL					Assay Description Activation of human GIRK1/2 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay				Bioorg Med Chem Lett 29: 791-796 (2019) Article DOI: 10.1016/j.bmcl.2019.01.027
					More data for this Ligand-Target Pair