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Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-activated inward rectifier potassium channel 4' and Ligand = 'BDBM50532028'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))		BDBM50532028
PNG
(CHEMBL4586820)
Show SMILES O=C(Cn1nnc(n1)-c1ccccc1)Nc1cc(nn1C1CCCCC1)C1CC1
Show InChI InChI=1S/C21H25N7O/c29-20(14-27-25-21(23-26-27)16-7-3-1-4-8-16)22-19-13-18(15-11-12-15)24-28(19)17-9-5-2-6-10-17/h1,3-4,7-8,13,15,17H,2,5-6,9-12,14H2,(H,22,29)
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PC cid
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Article
PubMed
n/an/an/an/a 659n/an/an/an/a



University of Nebraska Medical Center

Curated by ChEMBL


Assay Description
Activation of human GIRK1/4 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay

Bioorg Med Chem Lett 29: 791-796 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.027
BindingDB Entry DOI: 10.7270/Q2BV7M47
More data for this
Ligand-Target Pair