BDBM50532620 CHEMBL4440347

SMILES: FC(F)(F)c1cc(NC(=O)N[C@H]2CCN(C2)c2ccc3nncn3n2)ccc1Cl

InChI Key: InChIKey=XJFPWEGWVPIYIH-NSHDSACASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-C (Homo sapiens (Human))	BDBM50532620 (CHEMBL4440347) Show SMILES FC(F)(F)c1cc(NC(=O)N[C@H]2CCN(C2)c2ccc3nncn3n2)ccc1Cl |r| Show InChI InChI=1S/C17H15ClF3N7O/c18-13-2-1-10(7-12(13)17(19,20)21)23-16(29)24-11-5-6-27(8-11)15-4-3-14-25-22-9-28(14)26-15/h1-4,7,9,11H,5-6,8H2,(H2,23,24,29)/t11-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysis				ACS Med Chem Lett 7: 595-600 (2016) Article DOI: 10.1021/acsmedchemlett.6b00044
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50532620 (CHEMBL4440347) Show SMILES FC(F)(F)c1cc(NC(=O)N[C@H]2CCN(C2)c2ccc3nncn3n2)ccc1Cl |r| Show InChI InChI=1S/C17H15ClF3N7O/c18-13-2-1-10(7-12(13)17(19,20)21)23-16(29)24-11-5-6-27(8-11)15-4-3-14-25-22-9-28(14)26-15/h1-4,7,9,11H,5-6,8H2,(H2,23,24,29)/t11-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysis				ACS Med Chem Lett 7: 595-600 (2016) Article DOI: 10.1021/acsmedchemlett.6b00044
					More data for this Ligand-Target Pair