BDBM50532877 CHEMBL4458225

SMILES: Cl.C[C@H](N)C(=O)NCc1ccc(Oc2cccc3ccccc23)cc1

InChI Key: InChIKey=GVGFTBMHFSAYKL-UQKRIMTDSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50532877 (CHEMBL4458225) Show SMILES Cl.C[C@H](N)C(=O)NCc1ccc(Oc2cccc3ccccc23)cc1 |r| Show InChI InChI=1S/C20H20N2O2.ClH/c1-14(21)20(23)22-13-15-9-11-17(12-10-15)24-19-8-4-6-16-5-2-3-7-18(16)19;/h2-12,14H,13,21H2,1H3,(H,22,23);1H/t14-;/m0./s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of full-length Halo-tagged human CARM1 (1 to 608 residues) expressed in 293-F cells using [3H]-SAM and biotinylated histone peptides by sc...				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50532877 (CHEMBL4458225) Show SMILES Cl.C[C@H](N)C(=O)NCc1ccc(Oc2cccc3ccccc23)cc1 |r| Show InChI InChI=1S/C20H20N2O2.ClH/c1-14(21)20(23)22-13-15-9-11-17(12-10-15)24-19-8-4-6-16-5-2-3-7-18(16)19;/h2-12,14H,13,21H2,1H3,(H,22,23);1H/t14-;/m0./s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of PRMT6 (unknown origin)				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50532877 (CHEMBL4458225) Show SMILES Cl.C[C@H](N)C(=O)NCc1ccc(Oc2cccc3ccccc23)cc1 |r| Show InChI InChI=1S/C20H20N2O2.ClH/c1-14(21)20(23)22-13-15-9-11-17(12-10-15)24-19-8-4-6-16-5-2-3-7-18(16)19;/h2-12,14H,13,21H2,1H3,(H,22,23);1H/t14-;/m0./s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of full-length Halo-tagged human CARM1 (1 to 608 residues) expressed in 293-F cells using [3H]-SAM and biotinylated histone peptides by sc...				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50532877 (CHEMBL4458225) Show SMILES Cl.C[C@H](N)C(=O)NCc1ccc(Oc2cccc3ccccc23)cc1 |r| Show InChI InChI=1S/C20H20N2O2.ClH/c1-14(21)20(23)22-13-15-9-11-17(12-10-15)24-19-8-4-6-16-5-2-3-7-18(16)19;/h2-12,14H,13,21H2,1H3,(H,22,23);1H/t14-;/m0./s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of PRMT6 (unknown origin)				J Med Chem 59: 6838-47 (2016) Article DOI: 10.1021/acs.jmedchem.6b00668
					More data for this Ligand-Target Pair