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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 6' and Ligand = 'BDBM50532877'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein arginine N-methyltransferase 6


(Homo sapiens (Human))
BDBM50532877
PNG
(CHEMBL4458225)
Show SMILES Cl.C[C@H](N)C(=O)NCc1ccc(Oc2cccc3ccccc23)cc1 |r|
Show InChI InChI=1S/C20H20N2O2.ClH/c1-14(21)20(23)22-13-15-9-11-17(12-10-15)24-19-8-4-6-16-5-2-3-7-18(16)19;/h2-12,14H,13,21H2,1H3,(H,22,23);1H/t14-;/m0./s1
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 800n/an/an/an/an/an/a



University of Toronto

Curated by ChEMBL


Assay Description
Inhibition of PRMT6 (unknown origin)


J Med Chem 59: 6838-47 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00668
BindingDB Entry DOI: 10.7270/Q2445QZC
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 6


(Homo sapiens (Human))
BDBM50532877
PNG
(CHEMBL4458225)
Show SMILES Cl.C[C@H](N)C(=O)NCc1ccc(Oc2cccc3ccccc23)cc1 |r|
Show InChI InChI=1S/C20H20N2O2.ClH/c1-14(21)20(23)22-13-15-9-11-17(12-10-15)24-19-8-4-6-16-5-2-3-7-18(16)19;/h2-12,14H,13,21H2,1H3,(H,22,23);1H/t14-;/m0./s1
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 800n/an/an/an/an/an/a



University of Toronto

Curated by ChEMBL


Assay Description
Inhibition of PRMT6 (unknown origin)


J Med Chem 59: 6838-47 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00668
BindingDB Entry DOI: 10.7270/Q2445QZC
More data for this
Ligand-Target Pair