BDBM50536476 CHEMBL4549233

SMILES: CC(c1ccc2ncccc2c1C)n1cnc2ncc(nc12)-c1cn[nH]c1

InChI Key: InChIKey=KPRYUTIGJPKIRQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536476   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50536476 (CHEMBL4549233) Show SMILES CC(c1ccc2ncccc2c1C)n1cnc2ncc(nc12)-c1cn[nH]c1 Show InChI InChI=1S/C20H17N7/c1-12-15(5-6-17-16(12)4-3-7-21-17)13(2)27-11-23-19-20(27)26-18(10-22-19)14-8-24-25-9-14/h3-11,13H,1-2H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
Shanghai Pharmaceuticals Holding Co., Ltd Curated by ChEMBL					Assay Description Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...				Bioorg Med Chem 24: 4281-4290 (2016) Article DOI: 10.1016/j.bmc.2016.07.019
					More data for this Ligand-Target Pair