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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50536476'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50536476
PNG
(CHEMBL4549233)
Show SMILES CC(c1ccc2ncccc2c1C)n1cnc2ncc(nc12)-c1cn[nH]c1
Show InChI InChI=1S/C20H17N7/c1-12-15(5-6-17-16(12)4-3-7-21-17)13(2)27-11-23-19-20(27)26-18(10-22-19)14-8-24-25-9-14/h3-11,13H,1-2H3,(H,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.70n/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...


Bioorg Med Chem 24: 4281-4290 (2016)


Article DOI: 10.1016/j.bmc.2016.07.019
BindingDB Entry DOI: 10.7270/Q2PN9949
More data for this
Ligand-Target Pair