BDBM50538507 CHEMBL4640601
SMILES: COc1ccc(cc1OC)-c1cnn2c(N)c(-c3ccccc3)c(OC3CCN(C)CC3)nc12
InChI Key: InChIKey=YZNIHXUBUWEUCM-UHFFFAOYSA-N
Data: 38 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coiled-coil domain-containing protein 6 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of CCDC6/RET (unknown origin) transfected in human LC2/ad cells assessed as reduction in cell viability incubated for 6 days by CellTiter ... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcr-Abl (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 870 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of BCR/ABL (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luc... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor/Nucleophosmin (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of NPM/ALK (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luc... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SRC (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of BLK (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytoplasmic tyrosine-protein kinase BMX (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of BMX (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of FGFR1 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of FGFR2 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >9.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of FGFR3 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 4 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of FGFR4 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SRC (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of FGR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 1 and 2 (Flt-1 and KDR) (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of FLT1 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of FLT3 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony stimulating factor receptor (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of FMS (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor I receptor (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of IGF1R (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin receptor (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of INSR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of JAK2 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of KDR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of KIT (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of LCK (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lyn (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of LYN (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MER intracellular domain/EGFR extracellular domain chimera (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of MER (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of MET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor alpha (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of PDGFRalpha (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
VHL/PDGFRB (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of PDGFRbeta (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage-stimulating protein receptor (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of RON (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of ROS (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein cereblon/Tyrosine-protein kinase SRC (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of SRC (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of SYK (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase receptor Tie-1 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of TIE1 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of TRKA (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NTRK1/NTRK2 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of TRKB (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotrophic tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of TRKC (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of TYRO3 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of ZAP70 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TEL/KDR (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of TEL/KDR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luc... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET (Homo sapiens (Human)) | BDBM50538507 (CHEMBL4640601) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of KIF5B-RET V804M mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs b... | ACS Med Chem Lett 11: 558-565 (2020) | |||||||||||
More data for this Ligand-Target Pair |