BDBM50540190 CHEMBL4648642

SMILES: CN(C)CC(=O)N1CCC(CC1)c1nsc(Nc2ncc(Sc3ccccn3)cc2Oc2ccccc2)n1

InChI Key: InChIKey=IRMFOFIIMCDJCM-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50540190 (CHEMBL4648642) Show SMILES CN(C)CC(=O)N1CCC(CC1)c1nsc(Nc2ncc(Sc3ccccn3)cc2Oc2ccccc2)n1 Show InChI InChI=1S/C27H29N7O2S2/c1-33(2)18-24(35)34-14-11-19(12-15-34)25-30-27(38-32-25)31-26-22(36-20-8-4-3-5-9-20)16-21(17-29-26)37-23-10-6-7-13-28-23/h3-10,13,16-17,19H,11-12,14-15,18H2,1-2H3,(H,29,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Array BioPharma Inc. Curated by ChEMBL					Assay Description Activation of glucokinase (unknown origin)				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair