BDBM50542603 CHEMBL4640934

SMILES: COc1ccc-2c(c1)N(c1ccc(NCCNC3CCOCC3)cc1)C(=O)C(C)(C)c1ncc(Cl)cc-21

InChI Key: InChIKey=ABCNBUMIKUDYJQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Parathyroid hormone receptor (Homo sapiens (Human))	BDBM50542603 (CHEMBL4640934) Show SMILES COc1ccc-2c(c1)N(c1ccc(NCCNC3CCOCC3)cc1)C(=O)C(C)(C)c1ncc(Cl)cc-21 Show InChI InChI=1S/C29H33ClN4O3/c1-29(2)27-25(16-19(30)18-33-27)24-9-8-23(36-3)17-26(24)34(28(29)35)22-6-4-20(5-7-22)31-12-13-32-21-10-14-37-15-11-21/h4-9,16-18,21,31-32H,10-15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at PTHR1 (unknown origin) expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-indu...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair