BDBM50542661 CHEMBL4646241

SMILES: OC(=O)c1ccc(cc1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O

InChI Key: InChIKey=DFSUFCXGSMOZJI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542661 (CHEMBL4646241) Show SMILES OC(=O)c1ccc(cc1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O Show InChI InChI=1S/C26H20ClN5O3/c27-19-5-8-22-18(13-19)14-21(30(22)12-2-1-10-28)16-31-24-15-29-11-9-23(24)32(26(31)35)20-6-3-17(4-7-20)25(33)34/h3-9,11,13-15H,1-2,12,16H2,(H,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	0.501	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020)
					More data for this Ligand-Target Pair