null
SMILES: CONC(=O)c1c(C)c(nc2ccc(F)cc12)-c1ccc(cc1)-c1ccccc1F
InChI Key:
PDB links: 1 PDB ID matches this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human)) | BDBM50554026 (CHEMBL4744558) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human DHODH | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127589 BindingDB Entry DOI: 10.7270/Q29G5RGH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |