BindingDB logo
myBDB logout

null

SMILES: CO[C@H](C)c1cc(ccn1)-c1noc(n1)[C@H](C)NC(=O)c1cc(nn1C)C(F)(F)F

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50557683   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium channel subfamily T member 1


(Homo sapiens)		BDBM50557683
PNG
(CHEMBL4758890)
Show SMILES CO[C@H](C)c1cc(ccn1)-c1noc(n1)[C@H](C)NC(=O)c1cc(nn1C)C(F)(F)F |r|
PDB

NCI pathway
Reactome pathway

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 778n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assay

Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00675
BindingDB Entry DOI: 10.7270/Q2QF8XJ0
More data for this
Ligand-Target Pair