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null

SMILES: Cc1c2nc(cc(Cl)c2cc2c(Cl)cc(nc12)C(O)=O)C(O)=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50575551
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50575551 (CHEMBL4876009) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as dynamic mass redistribution response by DMR assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01624 BindingDB Entry DOI: 10.7270/Q2T72N8P
TBA					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50575551 (CHEMBL4876009) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as desensitization of zaprinast-induced DMR response preincubated for 1 hr...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01624 BindingDB Entry DOI: 10.7270/Q2T72N8P
TBA					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50575551 (CHEMBL4876009) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human GPR35 receptor expressed in CHO-K1 cells assessed as desensitization of zaprinast-induced DMR response preincubated for 1 h...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01624 BindingDB Entry DOI: 10.7270/Q2T72N8P
TBA					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50575551 (CHEMBL4876009) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.10	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human GPR35 receptor expressed in CHO-K1 cells assessed as dynamic mass redistribution response by DMR assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01624 BindingDB Entry DOI: 10.7270/Q2T72N8P
TBA					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50575551 (CHEMBL4876009) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as reduction in dynamic mass redistribution response in presence of GPR35 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01624 BindingDB Entry DOI: 10.7270/Q2T72N8P
TBA					More data for this Ligand-Target Pair