| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 35 |
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| Ligand | BDBM50575551 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2125633 (CHEMBL4834978) |
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| IC50 | 3.5±n/a nM |
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| Citation |  Wei, L; Hou, T; Li, J; Zhang, X; Zhou, H; Wang, Z; Cheng, J; Xiang, K; Wang, J; Zhao, Y; Liang, X Structure-Activity Relationship Studies of Coumarin-like Diacid Derivatives as Human G Protein-Coupled Receptor-35 (hGPR35) Agonists and a Consequent New Design Principle. J Med Chem64:2634-2647 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 35 |
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| Name: | G-protein coupled receptor 35 |
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| Synonyms: | G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 34085.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_33695097 |
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| Residue: | 309 |
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| Sequence: | MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMT
NLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRH
PLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGF
YLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVR
LAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKS
QDSLCVTLA
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| BDBM50575551 |
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| n/a |
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| Name | BDBM50575551 |
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| Synonyms: | CHEMBL4876009 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H8Cl2N2O4 |
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| Mol. Mass. | 351.141 |
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| SMILES | Cc1c2nc(cc(Cl)c2cc2c(Cl)cc(nc12)C(O)=O)C(O)=O |
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| Structure | 
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