null

SMILES: COc1cc(ccc1C(O)=O)-c1cccc2c1CSC[C@@H](NC(=O)[C@@H](COC2=O)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N(C)C

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kelch-like ECH-associated protein 1 (Homo sapiens (Human))	BDBM50584859 (CHEMBL5070465) Show SMILES COc1cc(ccc1C(O)=O)-c1cccc2c1CSC[C@@H](NC(=O)[C@@H](COC2=O)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N(C)C |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by surface plasmon resonance based direct binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01975 BindingDB Entry DOI: 10.7270/Q2FJ2MQS
					More data for this Ligand-Target Pair
Kelch-like ECH-associated protein 1 (Homo sapiens (Human))	BDBM50584859 (CHEMBL5070465) Show SMILES COc1cc(ccc1C(O)=O)-c1cccc2c1CSC[C@@H](NC(=O)[C@@H](COC2=O)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N(C)C |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by isothermal titration calorimetry				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01975 BindingDB Entry DOI: 10.7270/Q2FJ2MQS
					More data for this Ligand-Target Pair