BDBM5183 2-Chloro-3-phenyl-6,7-dimethoxyquinoline::2-chloro-6,7-dimethoxy-3-phenylquinoline::Quinoline-Containing Inhibitor 17

SMILES: COc1cc2cc(c(Cl)nc2cc1OC)-c1ccccc1

InChI Key: InChIKey=JOYQLLBQXFUCSK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5183   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM5183 (2-Chloro-3-phenyl-6,7-dimethoxyquinoline | 2-chlor...) Show SMILES COc1cc2cc(c(Cl)nc2cc1OC)-c1ccccc1 Show InChI InChI=1S/C17H14ClNO2/c1-20-15-9-12-8-13(11-6-4-3-5-7-11)17(18)19-14(12)10-16(15)21-2/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5183 (2-Chloro-3-phenyl-6,7-dimethoxyquinoline | 2-chlor...) Show SMILES COc1cc2cc(c(Cl)nc2cc1OC)-c1ccccc1 Show InChI InChI=1S/C17H14ClNO2/c1-20-15-9-12-8-13(11-6-4-3-5-7-11)17(18)19-14(12)10-16(15)21-2/h3-10H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	7.5	4
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair