BDBM5187 2-(quinolin-4-ylmethylidene)propanedinitrile::4-Quinylidenemalononitrile::Quinoline-Containing Inhibitor 21

SMILES: N#C\[#6](=[#6]\c1ccnc2ccccc12)C#N

InChI Key: InChIKey=ZRTKQGYMBGEXIB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM5187 (2-(quinolin-4-ylmethylidene)propanedinitrile | 4-Q...) Show SMILES N#C\[#6](=[#6]\c1ccnc2ccccc12)C#N Show InChI InChI=1S/C13H7N3/c14-8-10(9-15)7-11-5-6-16-13-4-2-1-3-12(11)13/h1-7H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5187 (2-(quinolin-4-ylmethylidene)propanedinitrile | 4-Q...) Show SMILES N#C\[#6](=[#6]\c1ccnc2ccccc12)C#N Show InChI InChI=1S/C13H7N3/c14-8-10(9-15)7-11-5-6-16-13-4-2-1-3-12(11)13/h1-7H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.5	4
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair