null
SMILES: C[C@H](Oc1cc(c(F)cc1C(=O)Nc1c(C)n[nH]c1Cl)-n1cc(C)c(n1)C(C)(C)O)C(F)(F)F
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human)) | BDBM530463 ((S)-N-(5-Chloro-3-methyl-1H-pyrazol-4-yl)-5-fluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022070069 | n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KSB | |||||||||||
More data for this Ligand-Target Pair |