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SMILES: Fc1cc(ccc1-n1cccn1)S(=O)(=O)c1ccc(NC(=O)NCc2cccnc2)cc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 543214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM543214 (3-(4-{[3-fluoro-4-(1H-pyrazol-1- yl)benzene]sulfon...) Show SMILES Fc1cc(ccc1-n1cccn1)S(=O)(=O)c1ccc(NC(=O)NCc2cccnc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DN3
					More data for this Ligand-Target Pair