null
SMILES: Cn1ncc(c1Nc1cncc(OC2CC(F)(F)C2)n1)-c1ccc(cn1)-c1ccc(cc1)C1(CC1)C(O)=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM557823 (1-[4-[6-[5-[[6-(3,3-difluorocyclobutoxy)pyrazin-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 51.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of a compound to inhibit binding of a ligand (1-(4′-(4-(((benzyloxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1′-biphenyl]-4-... | Citation and Details BindingDB Entry DOI: 10.7270/Q26M3B1D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM557823 (1-[4-[6-[5-[[6-(3,3-difluorocyclobutoxy)pyrazin-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A cDNA encoding the human LPAR1 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U937 cells using Lipo... | Citation and Details BindingDB Entry DOI: 10.7270/Q26M3B1D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM557823 (1-[4-[6-[5-[[6-(3,3-difluorocyclobutoxy)pyrazin-2-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 49.6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo... | Citation and Details BindingDB Entry DOI: 10.7270/Q26M3B1D | |||||||||||
More data for this Ligand-Target Pair |