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SMILES: Oc1c2C(=O)N3[C@@H]4CC[C@@H](C4)O[C@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 589177   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Solute carrier family 22 member 2


(Homo sapiens (Human))		BDBM589177
PNG
(US11548901, Compound 45)
Show SMILES Oc1c2C(=O)N3[C@@H]4CC[C@@H](C4)O[C@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O |r,TLB:3:5:10:8.7|
Reactome pathway
KEGG

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PC cid
PC sid
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US Patent
n/an/a 137n/an/an/an/an/an/a


TBA

Assay Description
The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2SF310S
More data for this
Ligand-Target Pair