null

SMILES: CC1CNCCN1c1nc(C)cc(Nc2ccc3[nH]ncc3c2)n1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 598557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM598557 (N-(6-methyl-2-(2-methylpiperazin-1-yl)pyrimidin-4-...) Show SMILES CC1CNCCN1c1nc(C)cc(Nc2ccc3[nH]ncc3c2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP576K
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 [1-552] (Homo sapiens (Human))	BDBM598557 (N-(6-methyl-2-(2-methylpiperazin-1-yl)pyrimidin-4-...) Show SMILES CC1CNCCN1c1nc(C)cc(Nc2ccc3[nH]ncc3c2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP576K
					More data for this Ligand-Target Pair