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SMILES: Cc1cc(Nc2ccc3[nH]ncc3c2)nc(n1)N1CC2CC1CN2

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 598581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM598581 (N-(2-(2,5-diazabicyclo[2.2.1]heptan-2-yl)-6-methyl...) Show SMILES Cc1cc(Nc2ccc3[nH]ncc3c2)nc(n1)N1CC2CC1CN2 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP576K
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 [1-552] (Homo sapiens (Human))	BDBM598581 (N-(2-(2,5-diazabicyclo[2.2.1]heptan-2-yl)-6-methyl...) Show SMILES Cc1cc(Nc2ccc3[nH]ncc3c2)nc(n1)N1CC2CC1CN2 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP576K
					More data for this Ligand-Target Pair