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SMILES: C1C2CNCC1N2c1nc2COCc2c(Nc2ccc3[nH]ncc3c2)n1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598596   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 2 [1-552]


(Homo sapiens (Human))		BDBM598596
PNG
(2-(3,6-diazabicyclo[3.1.1]heptan-6-yl)-N-(1H-indaz...)
Show SMILES C1C2CNCC1N2c1nc2COCc2c(Nc2ccc3[nH]ncc3c2)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<0.100n/an/an/an/an/an/a


TBA

Assay Description
Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2MP576K
More data for this
Ligand-Target Pair