Found 3 hits for monomerid = 624969 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM624969
(US20230322745, Compound 41)Show SMILES CN(CCCn1cnc2cc(CNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)c3CCCc3c12)C1CC[C@@H](CC1)OC(=O)C(O)(c1cccs1)c1cccs1 |r,wD:14.14,37.45,(3.77,-6.18,;4.17,-4.7,;3.08,-3.61,;1.59,-4.01,;.5,-2.92,;-.98,-3.32,;-1.61,-4.72,;-3.14,-4.56,;-3.46,-3.06,;-4.8,-2.29,;-4.8,-.75,;-6.13,.02,;-7.46,-.75,;-8.8,.02,;-10.13,-.75,;-10.13,-2.29,;-11.46,.02,;-12.8,-.75,;-14.13,.02,;-14.13,1.56,;-15.46,2.33,;-12.8,2.33,;-12.8,3.87,;-11.46,4.64,;-11.46,6.18,;-10.13,3.87,;-10.13,2.33,;-11.46,1.56,;-3.46,.02,;-3.14,1.53,;-1.61,1.69,;-.98,.28,;-2.13,-.75,;-2.13,-2.29,;5.66,-4.3,;6.06,-2.81,;7.54,-2.41,;8.63,-3.5,;8.23,-4.99,;6.75,-5.39,;10.12,-3.1,;10.52,-1.62,;9.43,-.53,;12.01,-1.22,;13.49,-.82,;12.4,.27,;11.44,1.47,;12.27,2.76,;13.76,2.36,;13.84,.82,;13.09,-2.31,;14.56,-1.83,;15.46,-3.08,;14.56,-4.32,;13.09,-3.85,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | n/a | 13.8 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human)) | BDBM624969
(US20230322745, Compound 41)Show SMILES CN(CCCn1cnc2cc(CNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)c3CCCc3c12)C1CC[C@@H](CC1)OC(=O)C(O)(c1cccs1)c1cccs1 |r,wD:14.14,37.45,(3.77,-6.18,;4.17,-4.7,;3.08,-3.61,;1.59,-4.01,;.5,-2.92,;-.98,-3.32,;-1.61,-4.72,;-3.14,-4.56,;-3.46,-3.06,;-4.8,-2.29,;-4.8,-.75,;-6.13,.02,;-7.46,-.75,;-8.8,.02,;-10.13,-.75,;-10.13,-2.29,;-11.46,.02,;-12.8,-.75,;-14.13,.02,;-14.13,1.56,;-15.46,2.33,;-12.8,2.33,;-12.8,3.87,;-11.46,4.64,;-11.46,6.18,;-10.13,3.87,;-10.13,2.33,;-11.46,1.56,;-3.46,.02,;-3.14,1.53,;-1.61,1.69,;-.98,.28,;-2.13,-.75,;-2.13,-2.29,;5.66,-4.3,;6.06,-2.81,;7.54,-2.41,;8.63,-3.5,;8.23,-4.99,;6.75,-5.39,;10.12,-3.1,;10.52,-1.62,;9.43,-.53,;12.01,-1.22,;13.49,-.82,;12.4,.27,;11.44,1.47,;12.27,2.76,;13.76,2.36,;13.84,.82,;13.09,-2.31,;14.56,-1.83,;15.46,-3.08,;14.56,-4.32,;13.09,-3.85,)| | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.268 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM624969
(US20230322745, Compound 41)Show SMILES CN(CCCn1cnc2cc(CNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)c3CCCc3c12)C1CC[C@@H](CC1)OC(=O)C(O)(c1cccs1)c1cccs1 |r,wD:14.14,37.45,(3.77,-6.18,;4.17,-4.7,;3.08,-3.61,;1.59,-4.01,;.5,-2.92,;-.98,-3.32,;-1.61,-4.72,;-3.14,-4.56,;-3.46,-3.06,;-4.8,-2.29,;-4.8,-.75,;-6.13,.02,;-7.46,-.75,;-8.8,.02,;-10.13,-.75,;-10.13,-2.29,;-11.46,.02,;-12.8,-.75,;-14.13,.02,;-14.13,1.56,;-15.46,2.33,;-12.8,2.33,;-12.8,3.87,;-11.46,4.64,;-11.46,6.18,;-10.13,3.87,;-10.13,2.33,;-11.46,1.56,;-3.46,.02,;-3.14,1.53,;-1.61,1.69,;-.98,.28,;-2.13,-.75,;-2.13,-2.29,;5.66,-4.3,;6.06,-2.81,;7.54,-2.41,;8.63,-3.5,;8.23,-4.99,;6.75,-5.39,;10.12,-3.1,;10.52,-1.62,;9.43,-.53,;12.01,-1.22,;13.49,-.82,;12.4,.27,;11.44,1.47,;12.27,2.76,;13.76,2.36,;13.84,.82,;13.09,-2.31,;14.56,-1.83,;15.46,-3.08,;14.56,-4.32,;13.09,-3.85,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.201 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
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