BDBM64558 (5,7-dichloroquinolin-8-yl) thiophene-2-carboxylate::2-thiophenecarboxylic acid (5,7-dichloro-8-quinolinyl) ester::MLS000121674::SMR000119051::Thiophene-2-carboxylic acid 5,7-dichloro-quinolin-8-yl ester::[5,7-bis(chloranyl)quinolin-8-yl] thiophene-2-carboxylate::cid_700833::thiophene-2-carboxylic acid (5,7-dichloro-8-quinolyl) ester

SMILES: Clc1cc(Cl)c2cccnc2c1OC(=O)c1cccs1

InChI Key: InChIKey=XMAHHPKHWABKQE-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 64558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
heat shock protein 90 (Candida albicans)	BDBM64558 ((5,7-dichloroquinolin-8-yl) thiophene-2-carboxylat...) Show SMILES Clc1cc(Cl)c2cccnc2c1OC(=O)c1cccs1 Show InChI InChI=1S/C14H7Cl2NO2S/c15-9-7-10(16)13(12-8(9)3-1-5-17-12)19-14(18)11-4-2-6-20-11/h1-7H	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	192	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, fluconazole, Hsp90, Calcineurin, ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MC8XGG
					More data for this Ligand-Target Pair
calcineurin A1, putative (Candida dubliniensis CD36)	BDBM64558 ((5,7-dichloroquinolin-8-yl) thiophene-2-carboxylat...) Show SMILES Clc1cc(Cl)c2cccnc2c1OC(=O)c1cccs1 Show InChI InChI=1S/C14H7Cl2NO2S/c15-9-7-10(16)13(12-8(9)3-1-5-17-12)19-14(18)11-4-2-6-20-11/h1-7H	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>2.85E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2ZP44K0
					More data for this Ligand-Target Pair
heat shock protein 90 (Candida albicans)	BDBM64558 ((5,7-dichloroquinolin-8-yl) thiophene-2-carboxylat...) Show SMILES Clc1cc(Cl)c2cccnc2c1OC(=O)c1cccs1 Show InChI InChI=1S/C14H7Cl2NO2S/c15-9-7-10(16)13(12-8(9)3-1-5-17-12)19-14(18)11-4-2-6-20-11/h1-7H	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2GM85R4
					More data for this Ligand-Target Pair