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null
SMILES: Clc1ccc(CNC2CCN(Cc3ccccc3)CC2)cc1
InChI Key: InChIKey=NQBDQXKOFMTXFA-UHFFFAOYSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Inward rectifier potassium channel 2 (Mus musculus) | BDBM65867 ((1-benzyl-4-piperidyl)-(4-chlorobenzyl)amine | 1-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 3.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Heat shock factor protein 1 (Mus musculus) | BDBM65867 ((1-benzyl-4-piperidyl)-(4-chlorobenzyl)amine | 1-b...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | >2.60E+5 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2P55KXK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM65867 ((1-benzyl-4-piperidyl)-(4-chlorobenzyl)amine | 1-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Technology (Banaras Hindu University) Curated by ChEMBL | Assay Description Inhibition of human serum butyrylcholinesterase using BTCI as substrate pre-incubated for 10 mins followed by substrate addition and measured for 6 m... | Eur J Med Chem 167: 510-524 (2019) Article DOI: 10.1016/j.ejmech.2019.02.030 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Homo sapiens (Human)) | BDBM65867 ((1-benzyl-4-piperidyl)-(4-chlorobenzyl)amine | 1-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Technology (Banaras Hindu University) Curated by ChEMBL | Assay Description Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine iodide as substrate pre-incubated for 10 mins followed by substrate addi... | Eur J Med Chem 167: 510-524 (2019) Article DOI: 10.1016/j.ejmech.2019.02.030 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase 1 (Homo sapiens (Human)) | BDBM65867 ((1-benzyl-4-piperidyl)-(4-chlorobenzyl)amine | 1-b...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Technology (Banaras Hindu University) Curated by ChEMBL | Assay Description Inhibition of human BACE1 using as 7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid beta/A4 precursor protein 770 fragment 667-676-(2,4-dinitrophe... | Eur J Med Chem 167: 510-524 (2019) Article DOI: 10.1016/j.ejmech.2019.02.030 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
