BDBM68338 (2Z)-2-(phenylmethylene)-4,9-dihydro-3H-carbazol-1-one::(2Z)-2-(phenylmethylidene)-4,9-dihydro-3H-carbazol-1-one::(2Z)-2-benzal-4,9-dihydro-3H-carbazol-1-one::(2Z)-2-benzylidene-4,9-dihydro-3H-carbazol-1-one::BRD-K70731066-001-03-5::cid_11958790

SMILES: O=C1c2[nH]c3ccccc3c2CC\C1=C\c1ccccc1

InChI Key: InChIKey=JCUHEMJWSFFFOR-OWBHPGMISA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 68338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
heat shock protein 90 (Candida albicans)	BDBM68338 ((2Z)-2-(phenylmethylene)-4,9-dihydro-3H-carbazol-1...) Show SMILES O=C1c2[nH]c3ccccc3c2CC\C1=C\c1ccccc1 Show InChI InChI=1S/C19H15NO/c21-19-14(12-13-6-2-1-3-7-13)10-11-16-15-8-4-5-9-17(15)20-18(16)19/h1-9,12,20H,10-11H2/b14-12-	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	8.31E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, fluconazole, Hsp90, Calcineurin, ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MC8XGG
					More data for this Ligand-Target Pair
calcineurin A1, putative (Candida dubliniensis CD36)	BDBM68338 ((2Z)-2-(phenylmethylene)-4,9-dihydro-3H-carbazol-1...) Show SMILES O=C1c2[nH]c3ccccc3c2CC\C1=C\c1ccccc1 Show InChI InChI=1S/C19H15NO/c21-19-14(12-13-6-2-1-3-7-13)10-11-16-15-8-4-5-9-17(15)20-18(16)19/h1-9,12,20H,10-11H2/b14-12-	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>2.85E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2ZP44K0
					More data for this Ligand-Target Pair
heat shock protein 90 (Candida albicans)	BDBM68338 ((2Z)-2-(phenylmethylene)-4,9-dihydro-3H-carbazol-1...) Show SMILES O=C1c2[nH]c3ccccc3c2CC\C1=C\c1ccccc1 Show InChI InChI=1S/C19H15NO/c21-19-14(12-13-6-2-1-3-7-13)10-11-16-15-8-4-5-9-17(15)20-18(16)19/h1-9,12,20H,10-11H2/b14-12-	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2GM85R4
					More data for this Ligand-Target Pair