BindingDB logo
myBDB logout

null

SMILES: Nc1nc(Nc2cc(Cl)c(c(Cl)c2)-c2ccc(NC(=O)C3CCC(F)(F)CC3)cc2)n[nH]1

InChI Key: InChIKey=JAYCBQYDCFOMHX-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 70748   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C virus (HCV genotype 1a, isolate H))		BDBM70748
PNG
(US9693997, 250)
Show SMILES Nc1nc(Nc2cc(Cl)c(c(Cl)c2)-c2ccc(NC(=O)C3CCC(F)(F)CC3)cc2)n[nH]1
Show InChI InChI=1S/C21H20Cl2F2N6O/c22-15-9-14(28-20-29-19(26)30-31-20)10-16(23)17(15)11-1-3-13(4-2-11)27-18(32)12-5-7-21(24,25)8-6-12/h1-4,9-10,12H,5-8H2,(H,27,32)(H4,26,28,29,30,31)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 13n/an/an/an/a



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
Plasmids expressing HCV E1 and E2 envelope proteins of GT1a H77 strain (Proc Natl Acad Sci USA 1997 94:8738-43) or GT1b Con1 strain (Science 1999 285...

US Patent US9693997 (2017)


BindingDB Entry DOI: 10.7270/Q2833Q56
More data for this
Ligand-Target Pair