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SMILES: COc1ccc(cc1)-c1[nH]c2nccnc2c1CC=C

InChI Key: InChIKey=RYNPAHUWYURCCW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7363 (6-(4-methoxyphenyl)-7-(prop-2-en-1-yl)-5H-pyrrolo[...) Show SMILES COc1ccc(cc1)-c1[nH]c2nccnc2c1CC=C Show InChI InChI=1S/C16H15N3O/c1-3-4-13-14(11-5-7-12(20-2)8-6-11)19-16-15(13)17-9-10-18-16/h3,5-10H,1,4H2,2H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	30
Faculte de Medecine et de Pharmacie					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 46: 222-36 (2003) Article DOI: 10.1021/jm020319p BindingDB Entry DOI: 10.7270/Q2474820
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha/beta (Homo sapiens (Human))	BDBM7363 (6-(4-methoxyphenyl)-7-(prop-2-en-1-yl)-5H-pyrrolo[...) Show SMILES COc1ccc(cc1)-c1[nH]c2nccnc2c1CC=C Show InChI InChI=1S/C16H15N3O/c1-3-4-13-14(11-5-7-12(20-2)8-6-11)19-16-15(13)17-9-10-18-16/h3,5-10H,1,4H2,2H3,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	603	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibitory concentration against Glycogen synthase kinase-3				Bioorg Med Chem Lett 15: 395-9 (2005) Article DOI: 10.1016/j.bmcl.2004.10.060 BindingDB Entry DOI: 10.7270/Q2WH2SR0
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7363 (6-(4-methoxyphenyl)-7-(prop-2-en-1-yl)-5H-pyrrolo[...) Show SMILES COc1ccc(cc1)-c1[nH]c2nccnc2c1CC=C Show InChI InChI=1S/C16H15N3O/c1-3-4-13-14(11-5-7-12(20-2)8-6-11)19-16-15(13)17-9-10-18-16/h3,5-10H,1,4H2,2H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	30
Faculte de Medecine et de Pharmacie					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 46: 222-36 (2003) Article DOI: 10.1021/jm020319p BindingDB Entry DOI: 10.7270/Q2474820
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7363 (6-(4-methoxyphenyl)-7-(prop-2-en-1-yl)-5H-pyrrolo[...) Show SMILES COc1ccc(cc1)-c1[nH]c2nccnc2c1CC=C Show InChI InChI=1S/C16H15N3O/c1-3-4-13-14(11-5-7-12(20-2)8-6-11)19-16-15(13)17-9-10-18-16/h3,5-10H,1,4H2,2H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	30
Faculte de Medecine et de Pharmacie					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 46: 222-36 (2003) Article DOI: 10.1021/jm020319p BindingDB Entry DOI: 10.7270/Q2474820
					More data for this Ligand-Target Pair