BDBM74600 MLS000041448::N-(1-ethyl-8-methyl-3-pyrazolo[3,4-b]quinolinyl)-2-pyridinecarboxamide::N-(1-ethyl-8-methyl-pyrazolo[3,4-b]quinolin-3-yl)picolinamide::N-(1-ethyl-8-methyl-pyrazolo[3,4-b]quinolin-3-yl)pyridine-2-carboxamide::N-(1-ethyl-8-methylpyrazolo[3,4-b]quinolin-3-yl)pyridine-2-carboxamide::SMR000046228::cid_665268

SMILES: CCn1nc(NC(=O)c2ccccn2)c2cc3cccc(C)c3nc12

InChI Key: InChIKey=JSILHCOPEQNNFW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 74600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human))	BDBM74600 (MLS000041448 | N-(1-ethyl-8-methyl-3-pyrazolo[3,4-...) Show SMILES CCn1nc(NC(=O)c2ccccn2)c2cc3cccc(C)c3nc12 Show InChI InChI=1S/C19H17N5O/c1-3-24-18-14(11-13-8-6-7-12(2)16(13)21-18)17(23-24)22-19(25)15-9-4-5-10-20-15/h4-11H,3H2,1-2H3,(H,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	862	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair