BDBM7552 BAY 59-7939 Analog 11::US8822458, 17

SMILES: Clc1ccc(s1)C(=O)NC[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCCC1=O

InChI Key: InChIKey=CWYUNIAGLBIPIP-AWEZNQCLSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7552   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM7552 (BAY 59-7939 Analog 11 | US8822458, 17) Show SMILES Clc1ccc(s1)C(=O)NC[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCCC1=O |r| Show InChI InChI=1S/C19H18ClN3O4S/c20-16-8-7-15(28-16)18(25)21-10-14-11-23(19(26)27-14)13-5-3-12(4-6-13)22-9-1-2-17(22)24/h3-8,14H,1-2,9-11H2,(H,21,25)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	25
Bayer Intellectual Property GmbH US Patent					Assay Description The enzymatic activity of human factor Xa (FXa) was measured using the conversion of a chromogenic substrate specific for FXa. Factor Xa cleaves p-ni...				US Patent US8822458 (2014) BindingDB Entry DOI: 10.7270/Q2VH5MJ2
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM7552 (BAY 59-7939 Analog 11 | US8822458, 17) Show SMILES Clc1ccc(s1)C(=O)NC[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCCC1=O |r| Show InChI InChI=1S/C19H18ClN3O4S/c20-16-8-7-15(28-16)18(25)21-10-14-11-23(19(26)27-14)13-5-3-12(4-6-13)22-9-1-2-17(22)24/h3-8,14H,1-2,9-11H2,(H,21,25)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of factor 10a				J Med Chem 53: 6243-74 (2010) Article DOI: 10.1021/jm100146h BindingDB Entry DOI: 10.7270/Q2CR5VBB
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM7552 (BAY 59-7939 Analog 11 | US8822458, 17) Show SMILES Clc1ccc(s1)C(=O)NC[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCCC1=O |r| Show InChI InChI=1S/C19H18ClN3O4S/c20-16-8-7-15(28-16)18(25)21-10-14-11-23(19(26)27-14)13-5-3-12(4-6-13)22-9-1-2-17(22)24/h3-8,14H,1-2,9-11H2,(H,21,25)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	8.3	25
Bayer HealthCare AG					Assay Description The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...				J Med Chem 48: 5900-8 (2005) Article DOI: 10.1021/jm050101d BindingDB Entry DOI: 10.7270/Q2J38QR6
					More data for this Ligand-Target Pair