BDBM77108 CMX157-220

SMILES: C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(=O)OCCCOCCCC(O)=O

InChI Key: InChIKey=BVUXXEUGUMDDCP-GFCCVEGCSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 77108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 B HXB2-LAI-IIIB-BRU (Human immunodeficiency virus type 1 group M subtyp...)	BDBM77108 (CMX157-220) Show SMILES C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(=O)OCCCOCCCC(O)=O |r| Show InChI InChI=1S/C16H26N5O7P/c1-12(8-21-10-20-14-15(17)18-9-19-16(14)21)27-11-29(24,25)28-7-3-6-26-5-2-4-13(22)23/h9-10,12H,2-8,11H2,1H3,(H,22,23)(H,24,25)(H2,17,18,19)/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Chimerix, Inc. US Patent					Assay Description The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...				US Patent US9694024 (2017) BindingDB Entry DOI: 10.7270/Q2BV7DRT
					More data for this Ligand-Target Pair