BDBM81339 MorphGTP (8b)

SMILES: Nc1nc2n([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)C(O)C3O)c(nc2c(=O)[nH]1)N1CCOCC1

InChI Key: InChIKey=YYAPYNUGMUZNGD-YEFCAQKCSA-K

Data: 2 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 81339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
FtsZ (Aquifex aeolicus)	BDBM81339 (MorphGTP (8b)) Show SMILES Nc1nc2n([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)C(O)C3O)c(nc2c(=O)[nH]1)N1CCOCC1 |r| Show InChI InChI=1S/C14H23N6O15P3/c15-13-17-10-7(11(23)18-13)16-14(19-1-3-31-4-2-19)20(10)12-9(22)8(21)6(33-12)5-32-37(27,28)35-38(29,30)34-36(24,25)26/h6,8-9,12,21-22H,1-5H2,(H,27,28)(H,29,30)(H2,24,25,26)(H3,15,17,18,23)/p-3/t6-,8?,9?,12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79E+5	n/a	n/a	n/a	n/a	7.5	n/a
University of Amsterdam					Assay Description The binding affinities to FtsZ were determined by a fluorescent coupled assay for phosphate relase. In this GTPase studies, phosphate liberated durin...				Chem Biol 15: 189-99 (2008) Article DOI: 10.1016/j.chembiol.2007.12.013 BindingDB Entry DOI: 10.7270/Q2P849CR
					More data for this Ligand-Target Pair
FtsZ (Aquifex aeolicus)	BDBM81339 (MorphGTP (8b)) Show SMILES Nc1nc2n([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)C(O)C3O)c(nc2c(=O)[nH]1)N1CCOCC1 |r| Show InChI InChI=1S/C14H23N6O15P3/c15-13-17-10-7(11(23)18-13)16-14(19-1-3-31-4-2-19)20(10)12-9(22)8(21)6(33-12)5-32-37(27,28)35-38(29,30)34-36(24,25)26/h6,8-9,12,21-22H,1-5H2,(H,27,28)(H,29,30)(H2,24,25,26)(H3,15,17,18,23)/p-3/t6-,8?,9?,12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+5	714	n/a	n/a	n/a	7.5	n/a
University of Amsterdam					Assay Description The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...				Chem Biol 15: 189-99 (2008) Article DOI: 10.1016/j.chembiol.2007.12.013 BindingDB Entry DOI: 10.7270/Q2P849CR
					More data for this Ligand-Target Pair