BDBM92359 Gangleoidin, 4

SMILES: COc1cc2OC(=O)c3c(C)c(Cl)c(O)c(Cl)c3Oc2c(C)c1C(O)=O

InChI Key: InChIKey=WQNZSMVUUOVALR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 92359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 6 (Homo sapiens (Human))	BDBM92359 (Gangleoidin, 4) Show SMILES COc1cc2OC(=O)c3c(C)c(Cl)c(O)c(Cl)c3Oc2c(C)c1C(O)=O Show InChI InChI=1S/C17H12Cl2O7/c1-5-10-15(12(19)13(20)11(5)18)26-14-6(2)9(16(21)22)7(24-3)4-8(14)25-17(10)23/h4,20H,1-3H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yale University School of Medicine					Assay Description The labeled fragment can be distinguished from full-length MKK by a change in fluorescence polarization. MKK6 was used as a substrate because it cou...				Chem Biol 19: 875-82 (2012) Article DOI: 10.1016/j.chembiol.2012.05.013 BindingDB Entry DOI: 10.7270/Q22B8WN0
					More data for this Ligand-Target Pair