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SMILES: Cc1ccc(cc1)S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O

InChI Key: InChIKey=JRRARHJPRLAGNT-VWLOTQADSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9853   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9853
PNG
((2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O |r|
Show InChI InChI=1S/C28H30N4O6S/c1-18-12-14-19(15-13-18)39(36,37)32-27(29)30-16-6-11-25(26(33)34)31-28(35)38-17-24-22-9-4-2-7-20(22)21-8-3-5-10-23(21)24/h2-5,7-10,12-15,24-25H,6,11,16-17H2,1H3,(H,31,35)(H,33,34)(H3,29,30,32)/t25-/m0/s1
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MMDB

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MCE
PC cid
PC sid
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PubMed
 1.42E+4 -6.72n/an/an/an/an/a4.730



Pharmacor Inc



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 15: 1509-13 (2005)


Article DOI: 10.1016/j.bmcl.2004.12.068
BindingDB Entry DOI: 10.7270/Q2Z31WW4
More data for this
Ligand-Target Pair